NisinZ® Vegetal Nisin Z is a mixture of closely related antimicrobial polypeptides produced by strains of Lactococcus lactis subsp. Lactis. Recognized internationally as a well-defined, highly effective food antimicrobial agent with low toxicity and a well-established history of safe use. Over the past few decades, Nisin Z is FDA approved and generally regarded as a safe peptide with recognized potential for clinical use. Studies have reported that Nisin Z can prevent the growth of drug-resistant bacterial strains, such as methicillin-resistant Staphylococcus aureus, Streptococcus pneumoniae, Enterococci and Clostridium difficile. Nisin Z has anti-biofilm properties and can work synergistically in combination with conventional therapeutic drugs. In addition, like host-defense peptides, Nisin Z may activate the adaptive immune response and have an immunomodulatory role. Increasing evidence indicates that Nisin Z can influence the growth of tumors and exhibit selective cytotoxicity towards cancer cells.
At Handary, we provided NisinZ® Vegetal Nisin Z as an active antibacterial ingredient for therapeutic improvement and preservation in health care products.