NisinZ® P

Ultrapure Nisin Z
Code
0304
Pack Size
10gr/bottle
Price
€ 130.00(Get member price)
Quantity
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Documents    NisinZ® P (PDS0305)    NisinZ® P (MSDS0305)   
DESCRIPTION:
NisinZ® P is an ultrapure Nisin Z produced through fermentation using the bacterium Lactococcus lactis sourced from sauerkraut. Primarily, it serves as an active antimicrobial ingredient in dietary supplements and healthcare products. Additionally, it is being explored as a cancer therapeutic drug. 
 
KEY BENEFITS:
• Active antimicrobial ingredient in dietary supplements and cosmetics
• Cancer therapeutic drug (Clinical trial Phase)
• Prolonged shelf life and survival
• Cost-efficient in use
 
APPLICATION AREAS:
Food-grade NisinZ® P: Functions as a food antimicrobial, extending the shelf life of dietary supplements.
Cosmetic-grade NisinZ® P: Utilized in skincare products, such as Anti-Staphylococcal Mastitis Breast Cream, and oral health products like Anti-Oral Biofilm Toothpaste and Antiplaque Mouthrinse.
Pharmaceutical Food-grade NisinZ® P (Nisin ZP): Investigated for its potential as a cancer therapeutic drug (Clinic trial Phase, For additional information, please click HERE.) 
 
REGULATIONS:
Nisin is globally approved as a food antimicrobial, with examples including Nisin CAS#: 1414-45-5 (US FDA), E#: E234 (EU EFSA), INECS/ELINCS #: 215-807-5. It has received FDA Investigational New Drug (IND) approval under reference number 167461.

Related reference literatures:

Chuanjiang Zhao et al. (2023) Nisin (Nisin ZP) a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease.

Suyash M Patil et al. (2022) Nisin ZP, an Antimicrobial Peptide, Induces Cell Death and Inhibits Non-Small Cell Lung Cancer (NSCLC) Progression in vitro in 2D and 3D Cell Culture.

Avand A and et al. (2018) In vitro cytototoxic activity of a Lactococcus lactis antimicrobial peptide against breast cancer cells.  

Ahmadi S et al. (2017) The apoptotic impact of Nisin as a potent bacteriocin on the colon cancer cells. 

Kamarajan, Pachiyappan et al. (2015) Nisin ZP, a Bacteriocin and Food Preservative, Inhibits Head and Neck Cancer Tumorigenesis and Prolongs Survival.

Shin et al. (2015) Nisin inhibited growth of Gram-positive and Gram-negative oral pathogens and saliva-derived multispecies biofilms without cytotoxicity to human oral cells.
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